The Department of Molecular Biology at Massachusetts General Hospital is a part of both the research community of the hospital and the Division of Medical Sciences of the Harvard Graduate School of Arts and Sciences. We also have a strong connection with the Department of Genetics at Harvard Medical School, where most of our scientists hold concurrent appointments. Members of the Department carry out fundamental studies in bioinformatics, genetics, molecular biology, and related disciplines, on a variety of topics at the cutting edge of science and medicine. Our mission is to advance scientific breakthroughs for the benefit of Mass General’s patients and the worldwide community. Our central strategic priority is to hire the very best early-career scientists, and help them to build and leverage next-generation technologies to generate fundamental advances in biomedicine.
In the field of Molecular Biology the goal is to analyze and understand the molecular basis of biological processes. It concerns itself with the function of DNA/RNA sequences and the interaction between DNA, RNA and proteins. Furthermore, this field overlaps to a great extend with other areas of biology and chemistry, particularly biochemistry and genetics. One of the most important molecular biology methods is the polymerase chain reaction (PCR). It is used to exponentially amplify a specific segment of DNA for various downstream applications like DNA cloning (genetic engineering), gene expression analysis (RT-PCR, RT-qPCR), genetic fingerprinting (paternity testing, forensics), sequencing (Next generation sequencing) and others more.