Using Norethisterone acetate can come with several side effects some of which can be severe and need immediate medical attention. Sexual desire changes, menstrual flow changes, growth of facial hair, headache, swelling, fluid retention, irritability, nausea, weight gain or loss are some of the mild effects. More worrying side effects include discharge from the uterus, breast tenderness, abdominal and chest pains, severe headache, yellowing of the eyes, pain in the legs or groin, skin rashes, skin yellowing, hives, shortness of breath, itching, unusual fatigue, problems with speech and vision.
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A restricted class of OTC drugs also exists in the . This restricted class includes drugs such as pseudoephedrine, emergency contraception, and some Schedule V controlled substances. These products, while considered OTC, are kept behind the pharmacy counter and must be dispensed by a pharmacist pursuant to proper identification, age verification, and patient education. In March 2012, the FDA considered expanding the definition of nonprescription drugs to include cholesterol, blood pressure, asthma and birth control medications. This new Rx-to-OTC switch ruling is currently under review and commenting.