This application note describes the extraction of a range of amphetamine-type compounds from whole blood, prior to GC/MS analysis. A protocol that allows the simultaneous extraction of various other drugs of abuse classes: barbiturates, benzodiazepines, cocaine and opiates, is also evaluated.
ISOLUTE® SLE+ columns with 1 mL sample capacity are used to extract whole blood samples following a straightforward sample dilution. No protein precipitation or other pre-treatment is required prior to sample loading. The sample preparation procedure delivers clean extracts, good recoveries and RSD values and LLOQs from 10 ng/mL (analyte dependant).
Tags: 2C-B , 5-APB , 6-APB , Amphetamine , Amphetamines , Application Notes , BZP , Butylone , Clinical , Column , English , Ethylone , Forensic , GC-MS , MDA , MDEA , MDMA , MDPV , Mephedrone , Methamphetamine , Methcathinone , Methedrone , Methylone , Naphyrone , TFMPP , Whole blood , mCPP , pMMA