Like other AAS, boldenone is an agonist of the androgen receptor (AR).  The activity of boldenone is mainly anabolic , with a low androgenic potency. Boldenone will increase nitrogen retention, protein synthesis, increases appetite and stimulates the release of erythropoietin in the kidneys.  Boldenone was synthesized in an attempt to create a long-acting injectable metandienone , for androgen deficiency disorders. Boldenone acts similar to metandienone with fewer adverse androgenic effects. [ medical citation needed ] Although commonly compared to nandrolone , boldenone lacks progesterone receptor interaction and associated progestogenic side effects.
Typically, steroids are "stacked", or taken at the same time with other muscle building compounds. It is not uncommon to use several different steroids at the same time, along with other hormones such as growth hormone and insulin. Huge amounts of protein and supplements are also used at this time. In no particular order, the grocery list of a common bodybuilder will include: testosterone, generic drugstore testosterone, testosterone for horses, testosterone for whales, protein powder, protein powder with testosterone, protein powder with spam, creatine, human growth hormone, fat-guy-sweat, amino acids, a fine chamomile tea and spam.
Trenbolone is often touted as an anabolic steroid that has ‘harsh’ side effects and tends to frighten many individuals who are considering the use of this compound. First and foremost, it should be established that because Tren does not aromatize into Estrogen at any dosage, there is no risk for encountering Estrogenic side effects . The Trenbolone side effects of particular concern are its androgenic side effects, and other side effects that are not usually seen with any other anabolic steroids (such as insomnia, excessive sweating, etc.).