Corticosteroid eye drops for dogs

Betsy:
Some of the generic drops have become expensive because of consolidation. For example, generic pred forte drops used to be very inexpensive but now there are only two companies that make it and those two companies are owned by the same two large pharmaceuticals that own the branded medicines, hence the price of the generic is almost the same as the expensive branded options. The price of drugs does vary from one pharmacy to another and each insurance plan has its preferred drugs which cost much less for patients depending on the deals they have made with the manufactures. For example brand A might be priced well at one store because they have made a good deal with the manufacturer and made it their preferred drug while brand B would be expensive. Across town a different drug store chain might have a great price for B and a high price for A because they have make B their preferred drug and have a great volume price with the manufacturer.
Alas, it is hard to find a cost effective way to protect your eyes around cataract surgery.
God Bless,
Gary Foster

Clinical efficacy was evaluated in 2 randomized, double-masked, placebo-controlled trials in which subjects with an anterior chamber cell grade ≥ “2” (a cell count of 11 or higher) after cataract surgery were assigned to DUREZOL or placebo (vehicle) following surgery. One drop of DUREZOL or vehicle was self instilled either 2 times per day or 4 times per day for 14 days, beginning the day after surgery. The presence of complete clearing (a cell count of 0) was assessed 8 and 15 days post-surgery using a slit lamp binocular microscope. In the intent-to-treat analyses of both studies, a significant benefit was seen in the 4 times per day DUREZOL –treated group in ocular inflammation and reduction of pain when compared with placebo. The consolidated clinical trial results are provided below.

Corticosteroids will inhibit phospholipase A2 thereby preventing the generation of substances which mediate inflammation, for example, prostaglandins. Corticosteroids also produce a marked, though transient, lymphocytopenia. This depletion is due to redistribution of the cells, the T lymphocytes being affected to a greater degree than the B lymphocytes. Lymphokine production is reduced, as is the sensitivity of macrophages to activation by lymphokines. Corticosteroids also retard epithelial regeneration, diminish post-inflammatory neo-vascularisation and reduce towards normal levels the excessive permeability of inflamed capillaries.

“For several years I have suffered from Uveitis and Macula Odema in one eye. The Macula Odema has settled but the Uveitis is only controlled with Corticosteroid eye drops. I tried to gradually reduce the corticosteroid drops and replace them with the carnosine, but this was not entirely successful and after a visit to the Specialist I am back using the coticosteroid drops. I didn't know whether it would be of any value to use both at the same time. What the Carnosine did do was reduce the pressure and as both my parents had glaucoma I am very conscious of the need to keep the pressure down. So I may need to use the carnosine for that in the future and of course I realize that extended use of the steroid drops can cause cataracts.”

NDC 61314-637-10

Prednisolone Acetate Ophthalmic Suspension USP 1%

Rx only

STERILE
10 mL

SANDOZ

FOR TOPICAL OPHTHALMIC USE ONLY.

INGREDIENTS: Each mL contains:
Active: prednisolone acetate %.
Preservative: benzalkonium chloride %.
Vehicle: hypromellose.
Inactives: dibasic sodium phosphate, polysorbate 80, edetate disodium, glycerin, citric acid and/or sodium hydroxide (to adjust pH), purified water.

USUAL DOSAGE: Two drops topically in the eye(s) four times daily.

WARNING: Do not touch dropper tip to any surface, as this may contaminate the suspension.

Read enclosed insert.

SHAKE WELL BEFORE USING.

STORAGE: STORE UPRIGHT at 8° - 24°C (46° - 75° F).

Manufactured by
Alcon Laboratories, Inc.
Fort Worth, Texas 76134 for
Sandoz Inc.
Princeton, NJ 08540
Printed in USA

H13438-0214

LOT/EXP.:

Corticosteroid eye drops for dogs

corticosteroid eye drops for dogs

“For several years I have suffered from Uveitis and Macula Odema in one eye. The Macula Odema has settled but the Uveitis is only controlled with Corticosteroid eye drops. I tried to gradually reduce the corticosteroid drops and replace them with the carnosine, but this was not entirely successful and after a visit to the Specialist I am back using the coticosteroid drops. I didn't know whether it would be of any value to use both at the same time. What the Carnosine did do was reduce the pressure and as both my parents had glaucoma I am very conscious of the need to keep the pressure down. So I may need to use the carnosine for that in the future and of course I realize that extended use of the steroid drops can cause cataracts.”

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